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549 datasets found
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PMR2: supporting collaborative, reproducible, and discoverable science
New Zealand Universities FigshareMy poster from the ICSB 2014 meeting. ABSTRACT: Background: PMR2 is the software framework supporting the Physiome Repository (https://models.physiomeproject.org). All content of the Physiome Repository is stored in version-controlled workspaces and specific revisions of a workspace can be exposed with a persistent URL and customisable presentation via...Created 12 March 2019 • Updated 19 March 2019 -
Modularity and reuse with CellML and the Physiome Repository
New Zealand Universities FigshareSlides from my presentation on modularity and reuse at the "NORMSYS/ISBE Workshop: standards for data and model exchange in systems biology". Showing how the modularity and reuse aspects of CellML work with the physiome repository to enusre accurate provenance records and reproducible simulations across a distributed network of scientists.Created 12 March 2019 • Updated 19 March 2019 -
Modularity and reuse with CellML and the Physiome Repository
New Zealand Universities FigsharePresentation I gave at the Auckland Bioengineering Institute's Friday Forum on 26th of September 2014. Described a bit of background as to why modularity and reuse is important in modelling of biological systems and how CellML provides facilities to enable modellers to make use of modularity and reuse in their model descriptions. Also talked about how the...Created 12 March 2019 • Updated 19 March 2019 -
Are isomiRs real or junk?
New Zealand Universities FigshareVariants of microRNAs (isomiRs) are commonly reported but their functional significance has been debated. Our study demonstrates that isomiRs are not junk, and that they function cooperatively with parental miRNAs.Created 12 March 2019 • Updated 19 March 2019 -
Imperfect centered sites - a new mode of miRNA binding
New Zealand Universities FigshareIt is thought that interactions between miRNAs and mRNAs occur using the seed region at the 5' end of the miRNA. Our study demonstrates that imperfect sites in the center of the miRNA are not only very common, they are functional too.Created 12 March 2019 • Updated 19 March 2019 -
The anatomy of miRNA-mRNA interactions.
New Zealand Universities FigshareAlthough most published interactions involve the miRNA seed, many other modes of miRNA binding have been detected. As more and more categories are detected, it may be pointless to continue categorizing miRNA interactions based on the position of the nucleotides involved.Created 12 March 2019 • Updated 19 March 2019 -
Experimental methods of miRNA target detection.
New Zealand Universities FigshareThis figure illustrates the six major methods of experimentally determining miRNA binding sites in mRNAs: (a) genome editing of predicted binding sites; (b) reporter gene assays; (c) gene-expression after miRNA modulation; (d) degradome sequencing; (e) chromatin-linked immuno-precipitation; and (f) biotin-linked chromatography.Created 12 March 2019 • Updated 19 March 2019 -
Multiple paths to mature miRNAs.
New Zealand Universities FigshareThis schematic illustrates the major enzymatic steps required to process primary transcripts into mature miRNAs via the canonical and alternative pathways.Created 12 March 2019 • Updated 19 March 2019 -
Computational Tools for the Creation, Simulationand Dissemination of...
New Zealand Universities FigshareMy poster presented at Experimental Biology 2015. Abstract: We have developed a software suite for the creation, simulation, and dissemination of epithelial cell models. The suite, known as GET (Generalized Epithelial Transport), is freely available under an open-source license at: http://get.readthedocs.org. GET consists of a model creation tool, a...Created 12 March 2019 • Updated 19 March 2019 -
News (mostly) from Auckland - VPH-Share General Assembly 2015
New Zealand Universities FigsharePresentation I gave at the VPH-Share General Assembly 2015, Krakow, Poland. Wednesday, 29 April 2015.Created 12 March 2019 • Updated 19 March 2019 -
Monitoring the Impact of Social Policy, 1980–2001: Social Expenditure...
New Zealand Universities FigshareThe paper examines social spending in New Zealand over the period 1981 - 2001 using OECD social expensditure dataCreated 12 March 2019 • Updated 19 March 2019 -
Developing the Virtual Physiological Human: tools, techniques, and best...
New Zealand Universities FigsharePoster from the IEEE EMBS Conference 2015, held in Milan, Italy. Introduces some key technologies enabling the development of the Virtual Physiological Human as well as some new material being developed to introduce new doctoral students to computational physiology.Created 12 March 2019 • Updated 19 March 2019 -
WIPNZ2011: World Internet Project New Zealand
New Zealand Universities FigshareFrom 2007, the Institute of Culture, Discourse and Communication (ICDC) at AUT University is conducting a long-term survey to track trends in Internet use, and to document the role and impact of the Internet in New Zealand society. The Internet has changed how business and trade deals are made; how schools and other academic institutions, councils, media...Created 12 March 2019 • Updated 19 March 2019 -
Research Data–Preserve, Share, Reuse, Publish, or Perish
New Zealand Universities FigshareSlides for a talk given on October the 5th, 2015, as part of the COMPASS Spring Seminar Series 2015 by Prof Mark Gahegan from the Centre for eResearch Abstract: Researchers need a variety of data services to support their work, from archives, to backups, through to data sharing and eventually data publishing. And it is very clear that our funding agencies...Created 19 March 2019 • Updated 19 March 2019 -
Surgical procedure for total knee arthroplasty in mice
New Zealand Universities FigshareDescription of the surgical procedure for total knee arthroplasty used to study impact of intraosseous regional administration of antibiotics.Created 19 March 2019 • Updated 19 March 2019 -
Stented Coronary Artery Haemodynamics from Computational Fluid Dynamics...
New Zealand Universities FigshareComputational fluid dynamics (CFD) comparison between two common stent designs regarding hemodynamic optimisation and minimising adverse flow induced vessel wall stresses.Created 12 March 2019 • Updated 19 March 2019 -
Scaled-Up Coronary Flow Measurement using Phase-Contrast MRI
New Zealand Universities FigshareTrue-scale CFD compared to scale-up phantom phase contrast MRI for patient-specific coronary flowCreated 12 March 2019 • Updated 19 March 2019 -
Research Data Management: University context (pt1)
New Zealand Universities FigsharePart 1 of 2 presentations to ACRSS on RDM service development at the University of Auckland.Created 12 March 2019 • Updated 19 March 2019 -
The Research Data Lifecycle
New Zealand Universities FigshareAn overview and data-centric view of the research process. The diagram is intended as a reference point or shared cognitive map to think about stages and transitions in data management and services.Created 12 March 2019 • Updated 19 March 2019 -
Ignite 2016 kiwifoo by Kubke
New Zealand Universities FigshareA take on what is the problem with current scientific publishingAt KiwiFoo 2016, Snells Beach, New ZealandCreated 12 March 2019 • Updated 19 March 2019
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