data test

Coefficients of the model fitted to the polyketide dose–BY4741 growth response curves.

Coefficients of the model fitted to the polyketide dose–Sf9 cell survival curves.

X-linked juvenile retinoschisis (XLRS) is a hereditary retinal dystrophy, caused by mutations in the RS1 gene which encodes the secreted protein retinoschisin. In recent years, several molecules have been proposed to interact with retinoschisin, including the retinal Na/K-ATPase, L-voltage gated Ca2+ channels, and specific sugars. We recently showed that...

Mean fluorescence intensity (MFI) from total cell population, calibrated against non-mutant ATP1B2. Given is the mean +/- SD of 3 (patch II region 4 T240A and S) or 4 (other patch II mutants) independent experiments. Neg. control: untransfected cells.

Amino acid (aa) positions and sequences of the each four regions building the predicted protein-protein-interfaces patch I and patch II of ATP1B2 as well as corresponding aa sequences in ATP1B1.

Mean fluorescence intensity (MFI) from total cell population, calibrated against non-mutant ATP1B2. Given is the mean +/- SD of 3 independent experiments. Neg. control: untransfected cells.

Characteristics of TMC patientsa and non -TMC patientsa.

The predicted change in the probability of being in each of HCU quarters following each additional telephone-based consultation.

Annualized healthcare utilization of TMC patientsa before and after first consultation.

Multivariable model of total annual health care costs of TMC patientsa (n = 107).

FindingsHere, we demonstrate that OP2113 (5-(4-Methoxyphenyl)-3H-1,2-dithiole-3-thione, CAS 532-11-6), synthesized and used as a drug since 1696, does not act as an unspecific antioxidant molecule (i.e., as a radical scavenger) but unexpectedly decreases mitochondrial reactive oxygen species (ROS/H2O2) production by acting as a specific inhibitor of ROS...

Radiology and PET reader scores.

BackgroundBoth 18F-fluoro-deoxy-glucose (FDG) positron emission tomography (PET), computed tomography (CT) and magnetic resonance imaging (MRI) are routinely used in the evaluation of memory clinic patients. Hybrid PET/MR systems now allow simultaneous PET and MRI imaging within the duration of the PET emission scan.PurposeTo compare the diagnostic yield...

Demographic and background information.

Changes in main clinical diagnosis.

Changes in main PET classification from PET/CT to PET/MRI.

Potential risk factors among MLP for emotional and behavioral problems within the LOLLIPOP cohort.

Risk of increased CBCL total, externalizing, and internalizing problem scores for potential risk factors at age 4: Results of univariable logistic regression analyses.

Odds ratios (OR) and 95% confidence intervals (CI) of the risk of increased CBCL total, externalizing, and internalizing problem scores for potential risk factors at age 4, adjusted for socio-economic status (SES) in multivariable analyses.

Referenzzustände bis 1990 für 61 Wald- und Forstökosystemtypen in Deutschland zur Beurteilung der ökologischen Integrität. Diese enthalten jeweils ein Datenblatt des Referenzzustandes mit Angaben zur Lebensraumfunktion, Netto-Primärfunktion, Kohlenstoffspeicherung, Nährstofffluss, Wasserfluss und Anpassungsfähigkeit an veränderliche Umweltbedingungen,...